Phase Genomics Blog

Bringing you the latest in Hi-C genomics, metagenomics, and other scientific musings.

Phase Genomics' mission is to bring you tools that make it easier to answer hard questions and make more discoveries. Part of that mission means sharing our knowledge, tips-and-tricks, successes and failures, and other thoughts with the community, as well as the experiences of other researchers using our tools to do great work. This blog covers the use of Hi-C and other chromatin conformation capture techniques for both genomics and metagenomics, as well as other new developments and trends in the genomics field.


April 1, 2022

Women’s History Month 2022

Women's History Month. Image of five women.

  Happy Women’s History Month! Being in the biotech industry and working with a strong, diverse team of scientists, we want to take a moment to reflect on the history of women in science and how we can make a brighter history for future generations. This past month, we shared stories from women at Phase... Read more »


January 19, 2022

Better together: long-range and long-read DNA sequencing methods close age-old blindspots in microbiome research

  Since its debut, next-generation sequencing has not rested on its laurels. Improved sequencing platforms have reduced error and lengthened reads into the tens of thousands of bases. The debut of ultra-long-range sequencing methods that are based on proximity ligation (aka Hi-C) has brought a new order-of-magnitude into reach by linking DNA strands with their neighbors... Read more »


January 10, 2022

A Year in Review: 2021

  A look back at the year 2021. The 21st year of the 21st century (a golden year, perhaps?) has come to an end. Looking back on the year that was abundant in vaccinations, canceled vacations, and virtual conferences, we would like to highlight the achievements that were made despite continuing challenges that face our... Read more »


December 15, 2021

Ultra-long-range sequencing technology expands research opportunities in reproductive genetics and oncology

  Phase Genomics’ recent release of the RUO cytogenomics platform, CytoTerra™, was accompanied by a webinar which covered an in-depth analysis of current technologies and emerging opportunities in reproductive genetics and oncology.     “The genome is the blueprint of life,” beginning the webinar, Ivan Liachko describes Phase Genomics’ history of discoveries and contributions to... Read more »


November 10, 2021

Inside the Microbiome Startup Industry

  “The microbiome is a very special opportunity because it allows you to create products that potentially have the efficacy of a drug, but the safety of a probiotic” -Colleen Cutcliffe, PhD   The Fall 2021 Genome Startup Day event, Inside the Microbiome, took a deep dive into the origins of several microbiome startups. Starting... Read more »


September 7, 2021

100 Publications

    Over 100 scientific papers have been published using Phase Genomics technology!   Since our founding in 2015, we have sought to bring transformative change to research, industry, and the clinic by building and providing cutting-edge genomic solutions to scientists all over the globe. Now, in 2021, we are happy to look back at... Read more »


July 26, 2021

Unlock the Virome with ProxiPhage

viruses moving through a net

  Metagenomic studies are illuminating the diverse array of microbiomes that exist from the ocean floor to our gastrointestinal tracts. Understanding these microbial communities is essential to understanding modern health and the environment; however, outdated lab techniques are laborious, costly, and fail to create a complete picture of the microbiome. This article, posted by Ivan... Read more »


June 3, 2021

Academia to Industry: What Students can Do to Prepare for Startup Career Paths

Five panelists speaking during online event

  “Try not to be a sociopath” – Robert Hayes, PhD A morsel of advice unanimously agreed upon by the panel of experts at the Spring Genome Startup Day event, good communication and empathy go a long way in startup environments. However, it takes more than a good attitude to flourish in this diverse and... Read more »


May 27, 2021

Better together: long-range and long-read DNA sequencing methods, combined, reach record heights in microbiome discovery

Microbiome plate and Phase Genomics logo. Reads "Breaking records in microbiome discovery"

  Click here for an updated blog post.   Since its debut, next-generation sequencing has not rested on its laurels. Improved sequencing platforms have reduced error and lengthened reads into the tens of thousands of bases. The debut of long-range sequencing methods that are based on proximity ligation (aka Hi-C) has brought a new order-of-magnitude... Read more »


April 29, 2021

New genome assembly method makes fruitful advances in genomic technology

  A collaboration between Phase Genomics and Pacific Biosciences of California is bringing about the next generation of genome assembly technology. A newly published software tool, FALCON-Phase, combines genomic proximity ligation methods developed by Phase Genomics™, with the high accuracy, long-read sequencing data from PacBio®, enabling researchers to create haplotype-resolved genome sequences on a chromosomal... Read more »