Delivering the world’s most complete genomes with Proximo Hi-C and ProxiMeta Hi-C
What we do
Phase Genomics creates the world's most complete genome and metagenome assemblies by using Hi-C to measure the physical structure of DNA molecules in vivo, bringing more than just sequence information to bear in genome assembly. Our 30-day turnaround shortens your path to complete genome assemblies, and our collaborative, flexible, and client-friendly approach is geared towards maximizing your satisfaction. Phase Genomics offers the easiest, fastest way to apply the power of Hi-C to your genomic and metagenomic projects.
PROXIMO CHROMOSOME-SCALE SCAFFOLDING
Phase Genomics' Proximo™ Hi-C scaffolding method is the best solution on the market able to create complete end-to-end genome scaffolds—even from short-read assemblies. Read more >
PROXIMETA METAGENOME DECONVOLUTION
Phase Genomics' ProxiMeta™ Hi-C metagenomic deconvolution method is a true revolution in microbial research, enabling complete genome assembly from raw mixed samples. Read more >
How it Works
Phase Genomics uses enhanced Hi-C technology that exploits in vivo chromatin proximity information to yield dramatically improved genome and metagenome assemblies.
SHORTEN THE PATH TO A COMPLETE GENOME
Our Proximo Hi-C Proximity-Guided Assembly process rapidly creates end-to-end genomes from any starting assembly. These high-quality genome assemblies give you the ability to reveal previously unreachable genomic information, such as linkage, fragmented genes, and structural discrepancies among strains and species.
ANALYZE YOUR DNA IN CONTEXT
Because our advanced Hi-C protocol captures proximity information in vivo, your genomic information retains biological and temporal context, allowing you to assess DNA associations within the intact cell. Phase Genomics enables you to make discoveries you couldn’t achieve any other way.
Phase genomics saves you time, effort, and money
With Phase Genomics, there’s no unproductive experimentation with diverse assembly methods, unnecessary processing or training costs, wasted sequencing runs, or slow incremental progress. From researchers who want reference-quality genomes on limited budgets to corporations developing industry-leading products, we enable new research capabilities.
PHASE GENOMICS WORKS WITH RAW TISSUE SAMPLES
Our patent-pending protocol requires no reference genome and works on raw samples containing intact cells, including field samples. You don’t need to purify high-molecular-weight DNA or perform other lab preparations. A typical project requires 0.5g of tissue with intact cells (or a comparable cell pellet) and no special collection, growing, or culturing steps required. Within a few weeks of receiving your sample, we will deliver your end-to-end chromosome scaffolds.
"The Phase Genomics team were definitely personally interested in our research. It wasn’t just a payment for service thing. They were genuinely interested in our results. It’s fun to work with people who are interested in the results."
– Dr. Catherine Peichel, Head of the Division of Evolutionary Ecology, University of Bern, Switzerland
DON'T PAY UNTIL YOU'RE HAPPY
Phase Genomics doesn't charge you a dime until you have results you're happy with. If you're not satisfied with our results, we'll work with you to identify problems and fix them at no additional cost, or you pay nothing. If you're not happy, we're not done.
WE WELCOME PROJECTS OF ANY SIZE
No matter the client, our team applies state-of-the art tools and methods in genome sciences, helping you interpret data, solve problems and communicate the results. Whether you have one project or a hundred, we're happy to provide you expert, personal service.
SIMPLY SEND US YOUR RAW SAMPLES
Whether you are a working in the field or in a lab, send us a small, raw tissue sample or a cell pellet and we'll give you complete genomes within a few weeks. Our methods require no reference genome and work with intact cells, eliminating the need for you to perform cumbersome DNA extraction techniques.
WE SUPPORT A WIDE RANGE OF APPLICATIONS
Our Proximity-Guided Assembly Hi-C platform creates the highest quality genome and metagenome assemblies available. These assemblies empower researchers to make powerful discoveries in fields such as agriculture, human health, food safety, pharmaceuticals, and biotechnology.