Blueprints for
  • Biology
  • Oncology
  • Cytogenomics
  • Metagenomics
  • Epigenomics

DNA encodes the exquisite complexity of life.

Massively parallel shotgun sequencing is only uncovering a part of the story. Unlock an added dimension with our ultra-long-range genome sequencing technology and computational tools, to help deliver on the promise of genomics.

Detect all major types of chromosomal abnormalities (structural variants) in a single,
NGS-based assay; analyze genome and chromatin architecture; unlock information stored in FFPE samples; characterize TADs; advance precision oncology.

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Deconvolute complex metagenomic samples; discover new species, strains and genes; attribute mobile genetic elements to their hosts; study the human microbiome, infectious disease, antibiotic resistance and gene function.

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Construct high-quality, chromosome-scale reference genomes; resolve haplotypes and polyploidy; compare and study gene structure, function and interactions; understand biology and evolution to conserve and protect biodiversity.

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Deeper Insights

Our ultra-long-range sequencing technology (enabled by proximity ligation) and computational tools enable you to generate direct, quantitative evidence of the spatial relationships between DNA sequences in vivo. This enables deeper insights into the architecture, variation, function, and complexity of genomes, epigenomes, and metagenomes.

What is ultra-long-range sequencing?
How does it work?

Our Technology

Complete sample-to-insight
solutions

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Read the latest in research
featuring proximity ligation

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Join the fast-growing
Phase community

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News: Phase Genomics Named
Metagenomics Innovation
Of The Year for 2023 by
BioTech Breakthrough Awards

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  • “We’ve generated and sequenced more than 70 Phase Genomics libraries so far, leading to numerous highly contiguous plant genomes and chromatin interaction projects. We are incredibly happy with our long-standing relationship with Phase, and look forward to our continued collaborations”

    Prof. Alex Harkess

    Assistant Professor: Auburn University & Faculty Investigator: HudsonAlpha Institute for Biotechnology
  • “The direct association of mobile genetic elements with their microbial hosts in complex populations is one of the last remaining technological challenges in the microbiome space. Proximity ligation is an elegant way to overcome this obstacle and presents a promising key technology in the study of bacteriophage and antibiotic resistance biology within a microbial context.”

    Prof. Paul Plummer

    Iowa State University and Executive Director of the Institute for Antimicrobial Resistance Research and Education
  • “The level of genome completeness and contiguity yielded by this technology has transformed how we view genome projects and has enabled us to ask new biological questions.”

    Prof. Jeff Maughan

    Department of Plant & Wildlife Sciences, Brigham-Young University
  • “The thing that was fun was that [the Phase Genomics team] were definitely personally invested in our research. It wasn’t just a payment for service thing. They were genuinely interested in our results. It’s fun to work with people who are interested in the results.”

    Prof. Dr. Catherine (Katie) Peichel

    Head: Division Evolutionary Ecology, University of Bern
  • “Metagenomics has drastically accelerated virus discovery, changing our view of virus sequence space from a few hundred viruses to millions. However, the twin grand challenge — to capture full genomes and to link newly discovered viruses to their hosts — are major roadblocks for the field. Promisingly, these early findings suggest that Phase Genomics’ proximity ligation approach may solve both these problems.”

    Matthew Sullivan

    Professor of Microbiology at Ohio State University and Founding Director of OSU’s Center of Microbiome Science

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Curious to learn how you can integrate ultra-long-range sequencing in your project?

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