September 1, 2017
Orphan Crop Gains Reference Genome with Proximo Hi-C
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Amaranth genome assembly brought to the chromosome-scale using Phase Genomics’ Proximo Hi-C technology. “Orphan crops” are growing in popularity because they have the potential to feed the world’s expanding population. You may have heard of orphan crops like quinoa or spelt, but have you heard of amaranth? The amaranth genus (Amaranthus) is a hearty... Read more » |
August 11, 2017
Threespine Stickleback Genome Upgraded Using Proximo™ Hi-C
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Proximo Hi-C genome scaffolding not only improved the well-studied threespine stickleback assembly, but also found structural differences that would have otherwise been missed. This week researchers from the University of Bern and the University of Georgia released a new high-quality reference threespine stickleback genome. The results of this project, a joint collaboration between Dr.... Read more » |
July 7, 2017
Spotlight on Hi-C in Science: New Technologies Boost Genome Quality
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Science writer, Elizabeth Pennisi, outlines available genomics technologies that are helping researchers improve genome assemblies with a focus on Hi-C’s ability to bring genome assembly to the chromosome-scale. This article, by Elizabeth Pennisi, focuses on how new technologies are making genome quality much better. Long-reads, optical maps, and Hi-C data are being synergistically applied to... Read more » |
April 27, 2017
Hi-C Used to Assemble Extremely Large, Difficult Barley Genome
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Barley is the 4th most cultivated plant in the world and has been a reliable food source for over 10,000 years. Genome Web reports on the exceptional state of the genome assembly and how researchers used Hi-C technology to tackle this extremely complex genome. The barley genome, like many other grains, is notorious for... Read more » |
March 29, 2017
Spotlight on Hi-C in The Atlantic: The Game-Changing Technique That Cracked the Zika-Mosquito Genome
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One of the most prolific science writers, Ed Yong, profiles how Hi-C sequencing technologies can make genome assembly easier and more cost-effective than ever before. Science writer Ed Yong covers the narrative on the researchers’ tackling the disease carrying Aedes aegypti genome, and how Hi-C “knitted” the genome from 36,000 pieces into complete and contiguous... Read more » |
March 6, 2017
Papadum’s Recipe for an Outstanding, Chromosome-Scale Genome with Hi-C
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Meet Papadum the Goat! Papadum is a descendent from a rare population of goats that used to inhabit the San Clemente Island, and notably, Papadum also now holds the world record for the most contiguous non-model mammalian genome. The recipe for a his amazing de novo genome assembly? Long reads, optical mapping, and Proximo Hi-C genome... Read more » |