Tag: epigenetics

Phase Genomics and QIAGEN Partner to Bring Hi-C Epigenetics Solutions to U.S. Market

Posted on October 29, 2020 by - Hi-C

In the last few years, Hi-C technology has grown in popularity within the epigenetics community. The chief application this proprietary method is to measure the three-dimensional architecture of genomes to better understand complex nuclear dynamics. Being a leader in this space, we at Phase Genomics seek to maximize the commercial footprint of our technology. As interest in this method has increased significantly, we have partnered with QIAGEN to increase its commercial availability. Read about the new EpiTect Hi-C kits available now through our collaborative effort.

 

QIAGEN expands its existing Epigenomic offering in the United States with Sample to Insight solution for Hi-C NGS analysis

• EpiTect Hi-C Kit helps researchers to better understand key aspects of long-range genome architecture
• License agreement enables QIAGEN to sell Phase Genomics’ proprietary proximity-ligation technology in the United States research market
• Adds to QIAGEN’s epigenomic capabilities in identification of individual methylation marks and histone modification at the nucleotide level

 

Hilden, Germany, and Germantown, Maryland, October 29, 2020 – QIAGEN today announced a non-exclusive agreement with Phase Genomics, Inc. to license specific patents to sell its EpiTect Hi-C kits in the United States. Through this agreement, QIAGEN now has access to support chromatin research in the largest research market in the world.

Chromatin conformation research, including chromatin conformational analysis (Hi-C), is an emerging and growing market area of genomic research that is refining our knowledge of the interconnectivity and organization of the genome. Hi-C has become a vital tool for understanding the structures and organization associated with cell biology. The EpiTect Hi-C Kit provides a simplified, single-box solution, requiring less than 250,000 mammalian cells to generate sequence-ready libraries.

“QIAGEN’s EpiTect portfolio has until now focused on identifying individual methylation marks and histone modification in the genome at the nucleotide level,” said Kerstin Steinert, Vice President of Product Development & Research Services at QIAGEN. “With the QIAGEN EpiTect Hi-C Kit, we are providing an end-to-end solution to study the 3-D genome and identify larger structural aspects of chromatin conformation and genomic architecture.”

“This partnership demonstrates a strong confidence in the value of Phase Genomics’ technology. Now, scientists studying epigenetics can more fully understand changes in genome architecture that may trigger disease in ways that are more cost-effective than ever before,” said Ivan Liachko, PhD, Founder and CEO of Phase Genomics. “Our Hi-C proximity-ligation technology, now available through QIAGEN, will help accelerate treatments to market and discover new paths toward the prevention of disease.”

In keeping with the QIAGEN commitment to provide Sample to Insight solutions, customers will have two options to analyze data from experiments. The EpiTect Hi-C Portal, located on GeneGlobe Data Analysis Center, provides multiple analysis types, including contact matrices and maps. In addition, Phase Genomics will provide a comprehensive suite of computational analytic services for Hi-C data analysis to QIAGEN EpiTect Hi-C Kit customers through a cloud-based bioinformatic platform that employs novel computational approaches and algorithms to analyze and interrogate proximity ligation (Hi-C) data.