Tag: review

A Year in Review: 2022

Text on orange and blue background reads: Phase Genomics, A Year in Review 2022

 

With 2023 well under way, here is a quick glimpse into the rearview mirror of Phase Genomics in 2022.

 

Last year was an exciting one for those of us in the genomics space. Exploring genomic interactions and refining methods to assemble the most complete genomes, the biotech sphere reached new heights and researchers uncovered new discoveries of our biological world. The use of AI boomed this year as developers set out to unravel complex problems in both everyday life and life sciences. Wielding these tools, we made significant progress in understanding plant and animal genomes, viromes, interactomes, and their relation to health and disease. 

 

These advancements have the potential to revolutionize the way we approach a wide range of medical conditions spanning viral infections, antimicrobial resistance, and cancer. As we move into the new year, we can look forward to even more exciting advances in genomics that will help us to close gaps in understanding and facilitate discoveries. Here’s a look at some proud moments from 2022.

 

Research Spotlights

Last year, we surpassed 150 papers published using our genome assembly technology. There’s a lot to share: advances have been made in a broad range of fields, from microbiology to oncology research, thanks to the researchers leveraging our technology. We appreciate their work and are thrilled to see their projects succeed! Here are some highlights from this year:

 

Published in Nature Biotechnology, breakthrough metagenomic research, featuring ProxiMeta Hi-C data, assembled over 400 high-quality MAGs and hundreds of host-viral/plasmid associations from a single fecal sample.

 

Genomic sequencing techniques unearthed surprises about life and evolution. This article features new studies that  illuminate a rarely-seen evolutionary transition in sex chromosomes. 

 

A study using ProxiMeta linked AMR genes to their genomic, plasmid, or viral host in microbiome samples. Their data was used to track horizontal gene transfer of antimicrobial resistance to Salmonella in chickens.

 

With so many projects being published in 2022, we couldn’t possibly capture everything in one blog, see all the new discoveries involving Phase Genomics here.

 

Company Highlights

From new products to new grants, 2022 was a big year for our team. Here’s a look at 2022’s news-worthy moments:

 

In the News

Podcasts

Genome Startup Day

Supporting Ukraine

  • We support humanitarian efforts in Ukraine because it is right and because it is personal – several team members have family residing in the country. Phase Genomics, along with many others in the biotech field, began sending aid to those suffering in this tragedy abroad. More here.
  • Charities we support: Razom for Ukraine, Voices of Children, UN Humanitarian Crisis Fund

 

Looking Forward to 2023

Thank you to everyone on our team, the amazing scientists using our tools, and our supporters for making these achievements possible. With 2023 already rolling in, we are hitting the ground running. Keep in touch with us on our social media accounts (Twitter, LinkedIn, YouTube) to stay updated on our new endeavors, recent research, and more news from our company.


Happy New Year from the Phase Genomics Team!

Photograph of Phase Genomics team outside

Year in Review: New Products, Projects, & Partnerships Amidst a Pandemic

 

Greetings from, mercifully, the beginning days of 2021.

As the world reels from Covid-19, all of our personal and professional lives have all been turned upside down. Despite this challenging environment, Phase Genomics has celebrated some big wins in 2020, amidst a tumultuous year. This year’s successes include releasing a dedicated Proximo Hi-C Kit for fungal samples, receiving $5.4M in grants, and announcing our licensing agreement with QIAGEN, among others. We want to thank our clients for their support, our incredible employees for their hard work, and the adaptability of leadership to maintain business operations throughout this unpredictable year. 

 

Here’s a quick look at our highlights from 2020:

 

New Products

Grants

Awards

Publications

In the News

Genome Startup Day 

Baby Boom!

    • Welcomed three new Phasebabies to the Phase Genomics team! 

 

See You (Fingers Crossed) in 2021!

In 2021, we are hopeful that we will be able to return to conferences and see our friends and clients in person. We plan to release exciting new features on our ProxiMeta microbiome platform, grow our team, and continue to serve all of our clients with cutting-edge tools, including some upcoming surprises. Follow Phase Genomics and the latest developments in our ecosystem in real-time on Twitter and LinkedIn or by subscribing to our quarterly newsletter – PhaseBook

We hope you had a safe, healthy, and relaxing Holiday Season and we look forward to seeing you in the New Year!

2019: A Year in Review with Phase Genomics

 

From scaling up the ProxiMeta Platform to publishing numerous Hi-C papers, Phase Genomics has had a year filled with new products, new discoveries, and new applications. Proximity ligation technology is continuing to fuel genomic and metagenomic research. Here is a brief recap of newsworthy items from 2019.  

 

Metagenomics Publications

MAY 30, 2019

The ISME Journal

Linking the Resistome and Plasmidome to the Microbiome »  

 

AUGUST 2, 2019

Genome Biology

Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation »  

 

SEPTEMBER 7, 2019

Frontiers in Microbiology

Degradation of recalcitrant polyurethane and xenobiotic additives by a selected landfill microbial community and its biodegradative potential revealed by proximity ligation-based metagenomic analysis »  

 

Genome Assembly Papers

FEBRUARY 7, 2019

BMC Genomics

Chromosome rearrangements shape the diversification of secondary metabolism in the cyclosporin producing fungus Tolypocladium inflatum »  

 

FEBRUARY 13, 2019

Journal of the American Society of Nephrology

Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci »  

 

MARCH 18, 2019

BioRxiv

Exceptional subgenome stability and functional divergence in allotetraploid teff, the primary cereal crop in Ethiopia »  

 

APRIL 15, 2019

BMC Genomics

A hybrid de novo genome assembly of the honeybee, Apis mellifera, with chromosome-length scaffolds »  

 

JUNE 3, 2019

GigaScience

A chromosome-scale assembly of the major African malaria vector Anopheles funestus »  

 

SEPTEMBER 16, 2019

BioRxiv

A de novo chromosome-level genome assembly of Coregonus sp. “Balchen”: one representative of the Swiss Alpine whitefish radiation »  

 

SEPTEMBER 16, 2019

BioRxiv

Chromosome-scale de novo assembly and phasing of a Chinese indigenous pig genome »  

 

OCTOBER 1, 2019

Communications Biology

Divergent evolutionary trajectories following speciation in two ectoparasitic honey bee mites »  

 

OCTOBER 1, 2019

KeyGene

KeyGene delivers first-ever fully phased red raspberry genome »  

 

NOVEMBER 8, 2019

Nature Communications

Emergence of the Ug99 lineage of the wheat stem rust pathogen through somatic hybridisation »  

 

NOVEMBER 25, 2019

New Zealand Journal of Crop and Horticultural Science

A whole genome assembly of Leptospermum scoparium (Myrtaceae) for mānuka research »  

 

DECEMBER 12, 2019

BioRxiv Preprint

Assembly of a young vertebrate Y chromosome reveals convergent signatures of sex chromosome evolution »  

 

DECEMBER 20, 2019

BioRxiv Preprint

Identifying the causes and consequences of assembly gaps using a multiplatform 2 genome assembly of a bird-of-paradise »  

 

Phase Genomics in the News

JANUARY 22, 2019

Market Insider 

Medicinal Genomics Releases Industry’s First Comprehensive Cannabis Reference Genome »  

 

JANUARY 23, 2019

Podcast: How to Live to 200

Dr. Ivan Liachko on Cat Poop and the Secrets of the Microbiome »  

 

FEBRUARY 25, 2019

Genome Web

Phase Genomics wins $200K grant to develop microbiome discovery technology »  

 

MARCH 6, 2019

Podcast: How On Earth

Dr. Ivan Liachko on Tagging the Bugs that Carry Antibiotic Resistance »  

 

APRIL 5, 2019

ZME Science

Saving the Honeybee: Can New Genomic Clues Help Solve the Colony Collapse Mystery? »  

 

APRIL 25, 2019

Genes to Genomes

Chromosome-scale genome assembly gives African mosquito and malaria vector fewer places to hide its secrets »  

 

MAY 9, 2019

The Genetic Literacy Project

Dissecting the cannabis genome in the quest for a better bud and effective medicines »  

 

JUNE 20, 2019

New Product 

Phase Genomics Accelerates Microbiome Discovery and Antibiotic Resistance tracking with New ProxiMeta8-Pack Including Bundled Analysis »  

 

AUGUST 6, 2019

New Application 

Phase Genomics’ Platform Links Viruses and Antibiotic Resistance Genes to the Microbiome in Study of a Highly Complex Microbial Community »  

 

SEPTEMBER 23, 2019

Xconomy

An Entrepreneur’s Quest to Make Seattle a Genome Sciences Hub »  

 

OCTOBER 22, 2019

Biodiesel Magazine

Phase Genomics awarded DOE grant for algae biofuel research »  

 

Blog Posts

JANUARY 13, 2019

The Era of Platinum Genomes Has Arrived »  

 

APRIL 5, 2019

Q&A with Co-Authors About Bees, Mites, and Their Genomes »  

 

APRIL 25, 2019

Q&A with Co-Author Dr. Nora Besansky about Malaria, Mosquitos, Insecticides and Adaptations! »  

 

MAY 8, 2019

The Highest-Quality Genomes: Q&A on Cannabis Genomics »  

 

JUNE 3, 2019

Project ProxiMeta: 2019 Metagenomics Award »  

 

JUNE 19, 2019

Dr. Ivan Liachko, LinkedIn Article: No longer beyond the horizon: Capturing the flow of antibiotic resistance genes through the microbiome with next-gen proximity ligation sequencing »  

 

AUGUST 7, 2019

Dr. Ivan Liachko, LinkedIn Article: A more complete microbiome: Using proximity-ligation next generation sequencing to uncover host-viral links in complex microbial ecosystems »  

 

SEPTEMBER 3, 2019

Choose This Year’s Metagenomics Award Winner »  

 

OCTOBER 28, 2019

Phase Genomics Transformative Genome Phasing Tool (FALCON-Phase) Now Compatible with Nanopore Sequencing »  

 

OCTOBER 29, 2019

Dr. Ivan Liachko, LinkedIn Article: Help Build Genome Startup Day 2020 »  

 

Phase Genomics Events and Awards

SEPTEMBER 23, 2019

Genome Startup Day

Phase Genomics hosted the inaugural Genome Startup day this year with an attendance of over two hundred scientists, students, and investors.   

 

SEPTEMBER 11, 2019

Project ProxiMeta Winner

Dr. Ben Tully: The Complete Hydrothermal Microbial Metal Metabolism »